Uses

This product is used to treat constipation. However, milder products (such as laxatives taken by mouth) should be used whenever possible for constipation. Bisacodyl is a stimulant laxative that works by increasing the amount of fluid/salts in the intestines. This effect usually results in a bowel movement within 15 to 60 minutes.

The normal frequency of bowel movements varies from once daily to 1 to 2 times weekly. Constipation is best treated by drinking plenty of fluids (four to six 8-ounce glasses daily), eating foods high in fiber, and exercising regularly.

This product is not recommended for use in children younger than 6 years unless directed by a doctor.

How To Use

This product is for rectal use only. Read and follow all directions on the product package or use as directed by your doctor. If you have any questions, ask your doctor or pharmacist. If the suppository is too soft to insert, chill in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

Wash your hands before and after using this product. Remove the foil wrapper. If desired, the suppository may be moistened with lukewarm water. Do not use petroleum jelly or mineral oil. Doing so may cause the product to be less effective. Lie on your left side with the right knee slightly bent. Gently insert the suppository, pointed end first, toward the navel and well up into the rectum. After insertion, stay in position for 15 to 20 minutes if possible until you feel a strong urge to have a bowel movement.

If this product is used too often, it may cause loss of normal bowel function and an inability to have a bowel movement without using the product (laxative dependence). If you notice symptoms of overuse such as diarrhea, abdominal pain, decreased weight, or weakness, contact your doctor promptly.

Consult your doctor promptly if you do not have a bowel movement after using this product or if you think you may have a serious medical problem.

Side Effects

Rectal irritation/burning/itching, mild abdominal discomfort/cramps, or nausea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this product do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• diarrhea that doesn't stop
• rectal bleeding/blisters

Diarrhea that doesn't stop may result in dehydration. Contact your doctor promptly if you notice any symptoms of dehydration such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using bisacodyl, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this product, tell your doctor or pharmacist your medical history, especially of:

• other bowel problems (such as blockage, ulcerative colitis, hemorrhoids, rectal bleeding)
• current stomach/abdominal symptoms (such as nausea/vomiting that doesn't stop, pain, cramping)

Consult your doctor before using this product if you have had a sudden change in bowel habits lasting more than 2 weeks, or if you need to use a laxative for more than 1 week. These could be symptoms of a serious medical problem.

This product may be used during labor/delivery to clean the bowels before the second stage of labor (pushing phase). At other times during pregnancy, this product should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are:

• other laxatives (including castor oil, stool softeners, lubricants such as mineral oil)

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Alberta residents can call PADIS (Poison and Drug Information Service) 24 hours a day at 1-800-332-1414. Canada residents can call a provincial poison control center.

Notes

Laxatives should be used only temporarily if needed for constipation. High doses or frequent use can lead to ongoing constipation and laxative dependence. (See also How to Use section.)

Missed Dose

Not applicable.

Storage

Refer to storage information on the package label. If you have any questions about storage, ask your pharmacist. Protect from heat, direct light, and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.