Faricimab is used to treat certain serious eye conditions (such as wet age-related macular degeneration, macular edema). It is used to help prevent decreased vision and blindness. Faricimab works by slowing the growth of abnormal new blood vessels in the eye and decreasing leakage from these blood vessels.

This medication is prepared and given by injection into the affected eye(s) by a health care professional. The affected eye is numbed before each injection. After the injection, you will remain in the doctor's office for a while, and your eye(s) and vision will be monitored.

The treatment schedule is based on your medical condition and response to treatment. Your doctor will give you regularly scheduled injections, usually once a month or every 4 weeks for the first 4 doses, and then as determined by your doctor. For the best effect, carefully follow your doctor's directions. Use this medication regularly to get the most benefit from it.

Tell your doctor if your condition gets worse.

Eye irritation or discomfort may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• floaters (blurry shapes that seem to float in front of your eyes)
• swollen eyelids

Get medical help right away if you have any very serious side effects, including:

• chest/jaw/left arm pain
• unusual sweating
• weakness on one side of the body
• trouble speaking
• confusion

This medication may rarely increase your risk for developing certain serious eye conditions (endophthalmitis, retinal detachment, retinal vasculitis). Get medical help right away if you notice any of these symptoms in the affected eye(s):

• pain
• redness
• sensitivity to light
• vision changes (such as blurred vision, loss of vision)

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using faricimab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• current eye infection/swelling

This drug may cause blurred vision. Do not drive, use machinery, or do anything that needs clear vision until you can do it safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using faricimab. Faricimab may harm an unborn baby. Your doctor should order a pregnancy test before you start this medication. Ask about reliable forms of birth control while using this medication and for 3 months after the last dose. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Medical tests (such as eye exams) should be done while you are using this medication. Keep all medical appointments. Consult your doctor for more details.

It is important to get each dose of this medication as scheduled. If you miss a dose, ask your doctor right away for a new dosing schedule.

Not applicable. This medication is given in a hospital or doctor's office and will not be stored at home.