Ribavirin is used in combination with other antiviral
medications (such as interferon, sofosbuvir) to treat chronic
(long-lasting) hepatitis C, a viral infection of the liver. Chronic
hepatitis C infection can cause serious liver problems such as scarring
(cirrhosis), or liver cancer. Ribavirin works by reducing the amount of
hepatitis C virus in your body, which may help your liver
recover.
It is not known if this treatment can prevent you from
passing the virus to others. Do not share needles, and practice "safer sex"
(including the use of latex condoms) to lower the risk of passing the virus
to others.
This section contains uses of this drug that are not
listed in the approved professional labeling for the drug but that may be
prescribed by your health care professional. Use this drug for a condition
that is listed in this section only if it has been so prescribed by your
health care professional.
This drug may also be used for severe acute respiratory
syndrome (SARS).
Read the Medication Guide provided by your pharmacist
before you start taking ribavirin and each time you get a refill. If you
have any questions, ask your doctor or pharmacist. Also read the drug
information for your other antiviral medication(s).
Take this medication by mouth as directed by your
doctor, usually twice daily with food.
The dosage and length of treatment is based on your age,
weight, medical condition, and response to treatment.
If this medication comes in a dosing package, carefully
follow the directions on the dosing package unless your doctor directs you
otherwise.
This medication works best when the amount of drug in
your body is kept at a constant level. Take this drug at evenly spaced
intervals. To help you remember, take it at the same times each
day.
Continue to take ribavirin and your other antiviral
medication(s) for the full length of time prescribed, even if your symptoms
disappear after a short time. Stopping any of the drugs too early may
result in a return of the infection.
Drink plenty of water while being treated with this
medication. Doing so will decrease the risk of serious side
effects.
Since this drug can be absorbed through the skin and
lungs and may harm an unborn baby, women who are pregnant or who may become
pregnant should not handle this medication or breathe the dust from the
tablets.
Nausea, diarrhea, stomach upset, headache, dizziness,
blurred vision, trouble sleeping, cough, low appetite, weight loss or gain,
dry skin, or changes in taste/hearing may occur. If any of these effects
last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed
because your doctor has judged that the benefit to you is greater than the
risk of side effects. Many people using this medication do not have serious
side effects.
Tell your doctor right away if you have any serious side
effects, including:
- unusual tiredness/weakness
- fast/pounding/irregular heartbeat
- muscle/joint pain
- vision changes
- easy bruising/bleeding
- dark urine
- yellowing of eyes/skin
Get medical help right away if you have any very serious
side effects, including:
- chest pain
- jaw/left arm pain
- stomach/lower back pain
- black/bloody stools
A very serious allergic reaction to this drug is rare.
However, get medical help right away if you notice any symptoms of a
serious allergic reaction, including:
- rash
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If
you notice other effects not listed above, contact your doctor or
pharmacist.
In the US - Call your doctor for medical advice about side effects.
You may report side effects to FDA at 1-800-FDA-1088 or at
www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about
side effects. You may report side effects to Health Canada at
1-866-234-2345.
Before taking ribavirin, tell your doctor or pharmacist
if you are allergic to it; or if you have any other allergies. This product
may contain inactive ingredients, which can cause allergic reactions or
other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or
pharmacist your medical history, especially of:
- blood disorders (such as sickle cell anemia, low hemoglobin,
thalassemia)
- kidney disease
- other liver problems (such as autoimmune hepatitis)
- heart disease
- high blood pressure
- breathing problems
- pancreas problems (such as pancreatitis)
- diabetes
This drug may make you dizzy or unusually tired or blur
your vision. Alcohol or marijuana (cannabis) can make you more dizzy or
tired. Do not drive, use machinery, or do anything that needs alertness or
clear vision until you can do it safely. Avoid alcoholic beverages. Talk to
your doctor if you are using marijuana (cannabis).
Older adults may be at greater risk for anemia while
using this drug.
Ribavirin must not be used during pregnancy. It is
recommended that female patients or female partners of male patients take a
pregnancy test before this medication is started. Pregnancy tests should
continue to be done while using this medication and for some time after
this medication is stopped (for 9 months for female patients and for 6
months for female partners of male patients). If you or your partner become
pregnant, or if you think you or your partner may be pregnant, tell your
doctor right away. See also Warning section.
Since this drug can be absorbed through the skin and
lungs and may harm an unborn baby, women who are pregnant or who may become
pregnant should not handle this medication or breathe the dust from the
tablets.
It is unknown if this drug passes into breast milk.
Consult your doctor before breastfeeding.
Drug interactions may change how your medications work
or increase your risk for serious side effects. This document does not
contain all possible drug interactions. Keep a list of all the products you
use (including prescription/nonprescription drugs and herbal products) and
share it with your doctor and pharmacist. Do not start, stop, or change the
dosage of any medicines without your doctor's approval.
Some products that may interact with this drug
include:
- antacids
- didanosine
- zidovudine
If someone has overdosed and has serious symptoms such
as passing out or trouble breathing, call 911. Otherwise, call a poison
control center right away. US residents can call 1-800-222-1222. Canada
residents can call 1-844-764-7669.
Do not share this medication with others.
Lab and/or medical tests (such as pregnancy, blood
counts/hemoglobin, liver/thyroid/heart function, EKG, eye exams) should be
done while you are taking this medication. Keep all medical and lab
appointments. Consult your doctor for more details.
This medication has been prescribed for your current
condition only. Do not use it later for another infection unless your
doctor tells you to.
If you miss a dose, use it as soon as you remember. If
it is near the time of the next dose, skip the missed dose. Use your next
dose at the regular time. Do not double the dose to catch
up.
Store at room temperature away from light and moisture.
Do not store in the bathroom. Keep all medications away from children and
pets.
Do not flush medications down the toilet or pour them
into a drain unless instructed to do so. Properly discard this product when
it is expired or no longer needed. Consult your pharmacist or local waste
disposal company.