This combination medication is used to treat symptoms caused by too much stomach acid such as heartburn, upset stomach, or indigestion. It is also used to treat symptoms of extra gas such as bloating and feelings of pressure/discomfort in the stomach/gut. Calcium carbonate is an antacid that works by lowering the amount of acid in the stomach. Simethicone works by breaking up gas bubbles in the gut.

Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

Take this product by mouth as directed. Chew the medication well before swallowing. Follow all directions on the product package. Do not take more than the maximum recommended dose stated on the product package. If you have any questions, ask your doctor or pharmacist.

Tell your doctor if your condition lasts or gets worse. Do not take the maximum dose of the medication for more than 2 weeks unless directed by your doctor. If you think you may have a serious medical problem, get medical help right away.

Constipation may occur. If this effect lasts or gets worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• loss of appetite
• nausea/vomiting
• unusual weight loss
• bone/muscle pain
• mental/mood changes (such as confusion)
• headache
• increased thirst/urination
• unusual weakness/tiredness
• signs of kidney problems (such as change in the amount of urine)

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking this medication, tell your doctor or pharmacist if you are allergic to calcium carbonate or simethicone; or if you have any other allergies. This product may contain inactive ingredients (such as soy), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

If you have any of the following health problems, consult your doctor or pharmacist before using this product:

• high calcium levels (hypercalcemia)
• stomach/intestinal blockage
• kidney disease (such as kidney stones)
• dehydration

This medicine may contain sugar. If you have diabetes, consult your doctor or pharmacist about using this drug safely.

If you are pregnant, tell your doctor before using this medication.

Calcium carbonate passes into breast milk. It is unknown if simethicone passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include:

• digoxin
• phosphate supplements (such as potassium phosphate)
• sodium polystyrene sulfonate

Calcium carbonate can decrease the absorption of other drugs. Some examples of affected drugs include tetracycline antibiotics (such as doxycycline, minocycline), bisphosphonates (such as alendronate), estramustine, iron, levothyroxine, pazopanib, strontium, quinolone antibiotics (such as ciprofloxacin, levofloxacin), among others. Separate your doses of these medications as far as possible from your doses of calcium carbonate. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.

Check the labels on all your prescription and nonprescription/herbal products (such as supplements, vitamins) because they may contain calcium. Ask your pharmacist about using those products safely.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669. Symptoms of overdose may include: nausea/vomiting, loss of appetite, mental/mood changes, headache, weakness, dizziness.

Keep all medical and lab appointments.

Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (such as avoiding caffeine/certain spices) may help to reduce heartburn and other stomach acid problems. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

Not applicable.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.