This combination of vitamins provides vitamin B-6, vitamin B-12 and folic acid to people who do not have enough of these vitamins for good health.

Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If stomach upset occurs, it may help to take this product with food.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. The dosage is based on your medical condition and response to treatment.

Nausea, stomach upset, diarrhea, drowsiness, flushing, and numbness/tingling may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• mental/mood changes
• unusual weakness

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before taking this medication, tell your doctor or pharmacist your medical history, especially of:

• certain blood disorders (such as pernicious anemia, other anemias)

This drug may make you drowsy. Alcohol or marijuana (cannabis) can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are:

• altretamine
• cisplatin
• levodopa (when used without carbidopa)
• folic acid antagonists (such as methotrexate)
• hydantoins (such as phenytoin, diphenylhydantoin)
• pyrimethamine

This product may interfere with certain lab tests (such as intrinsic factor antibodies, certain urobilinogen tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this product.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Do not share this medication with others.

Lab and/or medical tests (such as complete blood count, homocysteine levels) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

Remember that it is best to get your vitamins and minerals from healthy foods. Maintain a well-balanced diet and follow any dietary guidelines as directed by your doctor. B vitamins, including folic acid, are naturally found in leafy greens, other vegetables, and citrus fruits. Folic acid is also found in enriched grains such as bread, pasta and cereal.

Some brands of this medication may also contain ingredients such as vitamin E, para-aminobenzoic acid, or alpha-lipoic acid. Consult your doctor or pharmacist if you have questions about the ingredients in your brand.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.