This medication is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). Capsaicin works by decreasing a certain natural substance in your body (substance P) that helps pass pain signals to the brain.

This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This drug may also be used for nerve pain.

Use this medication on the skin only. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.

For the cream, gel, and lotion forms, apply a thin layer of medication to the affected area and rub in gently and thoroughly. You may want to use a cotton ball/swab or latex glove to apply the medication to avoid touching the medication with your hands.

If you are using the patch, peel off the protective covering and place the patch to cover the painful area. The patch is usually changed every 8 hours. Carefully follow the directions on your product package. Fold the used patch in half with the sticky sides together and discard out of reach of children and pets.

Do not apply the medication in the eyes, mouth, nostrils, or genitals. If you do get the medication in those areas, flush with plenty of water. Also, do not apply this medication to skin that is injured or irritated (for example, cut, scraped, sunburned).

Do not apply this medication immediately before or after activities such as bathing, swimming, sun bathing, or heavy exercise. Do not bandage or wrap the affected area or use a heating pad on that area. Doing so may increase the risk of side effects.

After applying the medication, wash your hands unless you are using this medication to treat the hands. If treating the hands, wait at least 30 minutes after applying the medication to wash your hands.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

This medication may sometimes take up to 2 months to work. Tell your doctor if your condition lasts for more than 7 days, if it gets worse, or if it keeps returning. If you think you may have a serious medical problem, get medical help right away.

Warmth, stinging, or burning on the application site may occur. If any of these effects last or get worse, contact your doctor or pharmacist promptly.

Coughing, sneezing, watery eyes, or throat irritation may occur if you breathe in the dried residue from the medication. Use caution to avoid inhaling the residue.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Stop using this medication and tell your doctor right away if you have any serious side effects, including:

• blistering/swelling at the application site
• increased/unusual pain at the application site

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using capsaicin, tell your doctor or pharmacist if you are allergic to it; or to zucapsaicin; or to hot peppers (from the Capsicum family); or to lidocaine or other local anesthetics that may be in your brand; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

If you have any health problems, consult your doctor or pharmacist before using this medication.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you are going to have an MRI test, tell testing personnel if you are using the patch. Some patches may contain metals that can cause serious burns during an MRI. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Capsaicin is very similar to zucapsaicin. Do not use medications containing zucapsaicin while using capsaicin.

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Keep all medical and lab appointments.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Refer to storage information printed on the package. If you have any questions about storage, ask your pharmacist. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.