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Transnasal Endoscopy (TNE): Before Your Procedure

A transnasal endoscopy (TNE) is a procedure that allows your doctor to look at the inside lining of your esophagus, your stomach, and the first part of your small intestine (duodenum). A thin, flexible viewing tool called an endoscope (scope) is used. The tip of the scope is inserted through your nose and then gently moved down your throat into the esophagus, stomach, and duodenum. Using the scope, your doctor can look for ulcers, inflammation, tumours, infection, or bleeding.

This procedure is another way to do an upper endoscopy. An upper endoscopy places the scope through your mouth. It uses medicines to help you relax, such as sedatives and anesthesia. A TNE (also called an unsedated transnasal endoscopy) doesn’t use the same medicines. People often have less preparation for this procedure and have a faster recovery. They also avoid the side effects from anesthesia.

How is it done?

It's done by a doctor with special training using an endoscope.

Medicine is applied to the nose and mouth to numb the area to keep you comfortable. A thin scope with a camera and light is placed into your nose and gently moved down your throat and into the esophagus, stomach, and small intestine. Small tools may be placed through the scope to take samples (biopsies) of tissue.

You’ll be able to breathe and talk during the procedure. It takes about 15 to 30 minutes.

How do you prepare?

Procedures can be stressful. This information will help you understand what you can expect. And it will help you safely prepare for your procedure.

Preparing for the procedure

  • Do not eat or drink anything for a few hours before the procedure. Follow your doctor's specific instructions. An empty stomach helps your doctor see your stomach clearly during the procedure. It also reduces your chances of vomiting.
  • Understand exactly what procedure is planned, along with the risks, benefits, and other options.
  • Tell your doctor ALL the medicines, vitamins, supplements, and herbal remedies you take. Some may increase the risk of problems during your procedure. Your doctor will tell you if you should stop taking any of them before the procedure and how soon to do it.
  • If you take aspirin or some other blood thinner, be sure to talk to your doctor. Find out if you should stop taking it before your surgery. Make sure that you understand exactly what your doctor wants you to do.
  • You will likely be able to drive after the procedure. But be sure you have someone to take you home if needed.

What are the risks?

Problems with this procedure are rare. The risks can include:

  • Mild nosebleeds.
  • Fainting.
  • Nausea or vomiting.
  • Nasal or throat pain.
  • Mild gastrointestinal bleeding.
  • A small hole in the esophagus, stomach, or small intestine.

Current as of: October 3, 2025

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

Care instructions adapted under licence by your healthcare professional. If you have questions about a medical condition or this instruction, always ask your healthcare professional. Ignite Healthwise, LLC disclaims any warranty or liability for your use of this information.