Uses

Oseltamivir is used to treat symptoms caused by the flu virus (influenza). It helps make the symptoms (such as stuffy nose, cough, sore throat, fever/chills, aches, tiredness) less severe and shortens the recovery time by 1-2 days.

This medication may also be used to prevent the flu if you have been exposed to someone who already has the flu (such as a sick household member) or if there is a flu outbreak in the community. Talk to your doctor for more details.

This medication works by stopping the flu virus from growing. It is not a substitute for the flu vaccine. (See also Notes section.)

How To Use

Read the Patient Information Leaflet if available from your pharmacist before you start taking this medicine. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth with or without food. You may take it with food or milk to minimize stomach upset. Take this medication as soon as flu symptoms appear or as soon as possible after you have been exposed to the flu. Oseltamivir works best if you start taking it within 2 days of either of these events.

Shake the bottle well before each dose. Your pharmacist will provide you with an oral dosing dispenser. Measure each dose carefully using the device as instructed. Be careful not to confuse the dose of oseltamivir in milligrams (mg) with the dose in milliliters (ml). Your pharmacist should show you exactly how much medication to use for each dose. Give the dose directly in the mouth. Do not mix with other liquids. After each use, rinse the dispenser with tap water and let it air dry. If you lose or damage the dosing dispenser, consult your pharmacist on what oral syringe you should use instead, and how to correctly measure the dose.

If you have the flu, take oseltamivir as directed by your doctor, usually twice a day for 5 days.

To prevent the flu, take oseltamivir as directed by your doctor, usually once a day for at least 10 days. Follow your doctor's instructions for how long to take this medicine.

The dosage is based on your medical condition, kidney function, and response to treatment. In children the dosage is also based on weight.

For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same time(s) every day. Continue to take this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection or failure to protect you from the flu.

Tell your doctor if your condition lasts or gets worse or if new symptoms appear.

Side Effects

Nausea and vomiting may occur. If either of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

The flu itself or oseltamivir may rarely cause serious mental/mood changes. This may be more likely in children. Tell your doctor right away of any signs of unusual behavior, including:

• confusion
• agitation
• self-injury

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking oseltamivir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• kidney disease (including dialysis treatment)

The liquid form of this medication may contain sorbitol. Sorbitol may cause upset stomach and diarrhea in people who have problems with certain sugars (fructose intolerance). Your doctor may need to order the capsule form of this medication if you cannot tolerate sorbitol.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor if you have received flu vaccine in the nose within 2 weeks before treatment with this medication. This medication may lower your protection from flu vaccine given in the nose. Wait at least 2 days after ending treatment with this medication before receiving flu vaccine given in the nose.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Alberta residents can call PADIS (Poison and Drug Information Service) 24 hours a day at 1-800-332-1414. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

This medication is not a substitute for the flu vaccine. Consult your doctor about the risks and important benefits of receiving a yearly flu shot to lower your chances of getting the flu.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

If you have questions about missing a dose or you don't have more medication, contact your healthcare provider or pharmacist.

Storage

Refrigerate the suspension and throw away any unused portion 17 days after mixed by the pharmacy. Do not freeze. This medicine may be stored at room temperature but will expire sooner than when refrigerated. If stored at room temperature, throw away any unused portion 10 days after mixed. Check the bottle or ask your pharmacist to see how long you can store this medicine at room temperature or in the refrigerator. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.